Showing posts with the label Genetic disorder

Cure for Psoriasis - a possiblity

Psoriasis (Photo credit: Wikipedia ) WebMD defines psoriasis as a "baffling and persistent skin disorder." With no real cure and treatment methods that have side effects, psoriasis can be a daunting condition to handle. Although, it is not a life threatening condition, it does reduce the quality of life and according to WHO estimates, affects more than 140 million people on the planet. Drugs, currently, in the market are primarily aimed at suppressing the immune system in general. So, although, symptoms reduce, the body is not putting up its best defense and the patient is prone to secondary infections. However, a promising study published in Science Translational Medicine might just enable us to treat psoriasis and not just symptomatically. But to understand this, we first need to look into what really happens in psoriasis. Psoriasis involves the abnormal production of skin cells due to a cascade of inflammatory responses which are triggered by Tumor Necrosis Fact

The story of Ringo, a dog who escaped Duchenne Muscular Dsytrophy!

By definition, a genetic disorder is one caused due to defects arising in genes . If you have inherited the defective gene or genes, then you are bound to be affected by the disorder. Image credit: Wikipedia A common example is Duchenne Muscular Dystrophy , caused in humans by a defective copy of the Dystrophin gene (DMD) that encodes the dystrohin protein. DMD gene is located on the X chromosome. Since, females in humans have two X chromosomes , one defective copy of the X chromosome makes the person a carrier for the disorder. Muscular Dystrophy  usually does not affect females, unless she is the progeny of an affected father and carrier mother. However, males, who inherit only one X chromosome from their mother, have a 50% chance of getting the defective copy of the gene from a carrier mother and therefore are at 50% risk of being affected by muscular dystrophy. That's the thumb rule. Meet Ringo, a male Golden Retriever, the exception!   Ringo, the Gol