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Showing posts with the label Genetic analysis

Severe Asthma Patients Respond Poorly To Common Treatment, Say The US Scientists

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Researchers at the Rutgers University and Genentech , US, have found that severe asthma patients do not respond to common medication treatment and have pointed to a solution to fix this problem. Image Credits: Pixabay Asthma patients are often prescribed corticosteroid inhalers. These drugs are a common treatment as they reduce swelling and inflammation of the airways to prevent asthma attacks and reduce their severity. These inhalers are effective in patients with mild to moderate asthma but people having severe asthma do not respond well to them. The research team investigated this problem and found the mechanism that seems to block the action of the drugs. For the study, they collected the samples of bronchial airway epithelial cells (BAECs) exposed to inhaled corticosteroids from three different groups: patients with severe asthma, patients with moderate asthma and healthy people. Then, they performed a genetic analysis to find which genes get activated in the cells in response t

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