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RotM: Interview with Dr. Suresh Thareja & Dr. Sant Kumar Verma

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For this edition of Researcher of the Month (RotM), we interviewed researchers Dr. Suresh Thareja and research fellow Sant Kumar Verma from Guru Ghasidas Central University located in Bilaspur, Chattisgarh, India.  Dr Thareja is the assistant professor for Pharmaceutical Chemistry in the School of Pharmaceutical Sciences at Ghasidas Central University and currently visiting scholar at the Georgia State University, USA. Mr. Sant Kumar Verma is the senior research fellow at the University working on management of diabetic complications. His research is being funded by the Indian Council of Medical Research (ICMR). 

Aldose reductase (AR) is an important enzyme since it converts glucose to sorbitol and begins the metabolism of glucose in the body. In patients, with diabetes, the body faces a hyperglycemic condition, which prompts the cells to make high amounts of AR, thereby producing high amounts of sorbitol which is impermeable in the cells and causes osmotic stress. Additionally, AR als…