Posts

Showing posts with the label Dogs

The story of Ringo, a dog who escaped Duchenne Muscular Dsytrophy!

Image
By definition, a genetic disorder is one caused due to defects arising in genes . If you have inherited the defective gene or genes, then you are bound to be affected by the disorder. Image credit: Wikipedia A common example is Duchenne Muscular Dystrophy , caused in humans by a defective copy of the Dystrophin gene (DMD) that encodes the dystrohin protein. DMD gene is located on the X chromosome. Since, females in humans have two X chromosomes , one defective copy of the X chromosome makes the person a carrier for the disorder. Muscular Dystrophy  usually does not affect females, unless she is the progeny of an affected father and carrier mother. However, males, who inherit only one X chromosome from their mother, have a 50% chance of getting the defective copy of the gene from a carrier mother and therefore are at 50% risk of being affected by muscular dystrophy. That's the thumb rule. Meet Ringo, a male Golden Retriever, the exception!   Ringo, the Gol