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Showing posts with the label BMAL1

Treat 2 genes to beat jet lag and cancer too! [Coffee-byte]

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The circadian clock is the clock that we were born with. As kids it helped us sleep and wake up on time and as adults it keeps us awake when we travel to different time zones. It is more efficient than any clock ever made by man for it keeps adjusting itself for every little change that we make and now we know how it works! 
The circadian clock has been associated with four genes, namely CLOCK, Period, Cryptochrome and BMAL1. It is the work of these genes (their respective proteins) that help us maintain our circadian rhythm. When a take a flight through different time zones, these genes take a while to adjust to new environs and this is why we experience 'jet-lag'. But researchers Rui Ye and Aziz Sancar at the University of North Carolina, were able to show that CLOCK and BMAL1 were the most important genes needed to maintain our circadian rhythms. Now, that we know how the clock works, we can design drugs that can help us to set the clock quicker or later as we need and get in…