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Severe Asthma Patients Respond Poorly To Common Treatment, Say The US Scientists

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Researchers at the Rutgers University and Genentech , US, have found that severe asthma patients do not respond to common medication treatment and have pointed to a solution to fix this problem. Image Credits: Pixabay Asthma patients are often prescribed corticosteroid inhalers. These drugs are a common treatment as they reduce swelling and inflammation of the airways to prevent asthma attacks and reduce their severity. These inhalers are effective in patients with mild to moderate asthma but people having severe asthma do not respond well to them. The research team investigated this problem and found the mechanism that seems to block the action of the drugs. For the study, they collected the samples of bronchial airway epithelial cells (BAECs) exposed to inhaled corticosteroids from three different groups: patients with severe asthma, patients with moderate asthma and healthy people. Then, they performed a genetic analysis to find which genes get activated in the cells in response t

Scientists Have Found That Asthma May Reduce the Risk of Brain Tumors

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   Photo by Robina Weermeijer on Unsplash Asthma is a condition in which a person’s airways become narrow, inflamed, and swell and generate extra mucus, making it difficult for him to breathe. This is a common disease.  Globally, 300 million people are estimated to be currently affected by this disease. Interestingly, a recent study conducted at the Washington University School of Medicine found that people with asthma are less prone to developing brain tumors. What Have Scientists Found?  T-cells are a part of the immune system that originate from stem cells in the bone marrow. Usually, these cells protect the body from infections but one can also find them in action when a person develops asthma. In the study, scientists found that asthma forces the T-cells to behave in a manner that causes lung inflammation but halts the growth of brain tumors.  The study available in Nature Communications proposed that reprogramming or altering T-cells in brain tumor patients could be a new way

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