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Although no one was injured, the loss of cargo and devastation at the launchpad would run into millions of dollars for NASA. The real estimate of loss will only be known after a complete analysis is done. The rocket, ferrying cargo to the ISS, was developed and operated by Orbital Sciences Corporation, which has already delivered cargo twice to the ISS. NASA has confirmed that there was no critical cargo on the flight and supplies on the ISS will not be affected by the failure of the mission.
But irrespective of the losses, the failure of the rocket launch teaches us one important thing about space research, that there is a lot more to learn!